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Hyperimmune serum against canine leptospirosis

Description:

The serum is used for passive immunization and in the treatment of dogs sick with leptospirosis. The serum is a transparent slightly opalescent liquid, pale yellow in colour, sometimes with a red hue. Minor grayish white protein precipitate may form upon storage and should suspend easily upon shaking.

Composition:

The serum contains antibodies to leptospira Canicola, Icterohaemorrhagiae and Grippotyphosa.

Mode of admnstration

Vials with the serum are thoroughly shaken and warmed in a water bath to 37-38°C.

The serum is administered singly via percutaneous route in shoulder blade region. The dose depends on the body weight (0,5 cm3 per 1 kg of weight). In severe cases of illness the serum is administered for the second time at half the indicated dose. The serum may also serve as a differential diagnostic tool. If no therapeutic effect is observed upon repeated injection, this would mean that the disease is of non-leptospiral origin.

Immunity:

Immunity develops 4 to 6 hours after vaccination and lasts 6 to 8 days.

Formulation:

The vaccine is available in vials (10 cm3/5 doses).

Shelf life:

48 months if kept in a dark dry place at a temperature between 2 and 10°C.

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